![]() Here, the authors identify the domains responsible for the eIF4E/human rhinovirus 2 2A(pro) interaction using molecular modelling and describe mutations that impair this interaction and delay in vitro cleavage of eIF4G isoforms. ![]() Title: Arginine methyltransferase inhibitor 1 inhibits gastric cancer by downregulating eIF4E and targeting PRMT5. PRMT1 inhibition prevents gastric cancer progression by downregulating eIF4E and targeting type II PRMT5. Xenopus tropicalis (tropical clawed frog)Īnopheles gambiae (African malaria mosquito) Alternative splicing results in multiple transcript variants. Several pseudogenes of this gene are found on other chromosomes. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. Biopharmaceutical Research and Development NewĮukaryotic translation initiation factor 4EĮukaryotic translation initiation factor 4E-like 1.GenScript DNA-Encoded Chemical Library Kit – GenDECL™.CRISPR Gene Editing Kits and Antibodies.Immune Checkpoint Antibodies and Proteins.Claudin 18.2 Proteins & Stable Cell Lines.Stable Cell Line (CellPower™) for Assay Development.Research Grade Lentiviral Vector Packaging New!.High-Throughput DNA Library Assembly Service.Gene to Lentivirus One Stop Package New!.TurboCHO™ Recombinant Expression System Upgraded. ![]() TurboCHO™ High Throughput Services as fast as 2 weeks. ![]()
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